Thrombopoietin Protein (THPO)
Aperçu rapide pour Thrombopoietin Protein (THPO) (ABIN935820)
Antigène
Voir toutes Thrombopoietin (THPO) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
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Attributs du produit
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Purified recombinant Human Thrombopoietin protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ? 1.0 ng/mL, corresponding to a specific activity of ? 1 x 10^6 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Thrombopoietin (THPO) protein (His tag)
THPO Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Thrombopoietin (THPO) (AA 22-195) protein (His-IF2DI Tag)THPO Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Thrombopoietin (THPO) (AA 23-195) protein (His tag)THPO Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Thrombopoietin (THPO) (AA 22-356) (Active) proteinTHPO Origine: Souris Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Thrombopoietin (THPO) (AA 1-349) protein (GST tag)THPO Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Thrombopoietin (THPO) proteinTHPO Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
Thrombopoietin (THPO) proteinTHPO Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant 97,00% SDS
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.
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Buffer
- Lyophilized from 10 mM sodium citrate, pH 3.0.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Thrombopoietin (THPO)
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Autre désignation
- Thrombopoietin
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Sujet
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TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and Mouse TPO exhibits cross-species reactivity.
Alternative Names: TPO protein, THPO protein, MGDF protein, c-MPL Ligand protein, Megakaryocyte colony-stimulating factor protein -
Poids moléculaire
- 18.6 kDa
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Pathways
- Signalistation JAK/STAT, Hormone Activity
Antigène
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